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Studies show FOXO4-DRI treatment reduces senescent cell burden by 50-70% in various tissues including liver, kidney, and adipose tissue within weeks of treatment initiation in aged mice

The April 2024 landmark paper proposing BPC-157 as a cytoprotection mediator with neurotransmitter-like activity provides an elegant theoretical framework, but elegance is not evidence

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doi: 10.1016/j.bioadv.2025.214410, 32