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Epidemiology (Cambridge, Mass)

Neurology 48 , 10771081 (1997)

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doi: 10.1172/JCI11991 120 GiridharanSSrinivasanM

The NAAG storage cycle provides a mechanism for cancer cells to store this important metabolic product by converting glutamate produced from glutamine into NAAG and then back into glutamate, thus providing a mechanism for storing this important metabolic product under stress conditions such as inhibition of glutamine breakdown [37] (Fig