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Another important consideration is that high-dose folic acid can mask the haematological signs of B12 deficiency while allowing neurological damage to progress

PAS is supporting research to explore more flexible and less resource-intensive methods, including: Self-Administration : Advocating for more patients (if they are willing) to be taught how to administer their own injections safely at home, reducing reliance on GP appointments

The structure has undergone significant changes as DISA has worked to reduce complexity and enhance understanding

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Given the lack of specific guidelines for the optimal treatment of vitamin B12 deficiency in individuals receiving metformin therapy, the MHRA [71] recommends following the National Institute for Health and Care Excellence (NICE) guidelines for managing vitamin B12 deficiency in the general population