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In segment (b) , inhibition of phosphoglucose isomerase could be bypassed by glyceraldehyde-3-phosphate and ribose, through the non-oxidative phase of the pentose phosphate pathway

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Two molecules of lactic acid contain exactly the same number of carbons, hydrogens, and oxygens as one molecule of glucose ( Fig

doi: 10.1182/blood-2012-11-427765 70 ZhangDLGhoshMCRouaultTA

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Synthesis and structureactivity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists