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Investigation of the influence of maternal antioxidant intake in pregnancy on the development of asthma and eczema in children showed that maternal vitamin E intake during pregnancy is negatively associated with wheeze in the absence of cold and childhood eczema in the childrens with 24 months of age (115)

Indeed, these are the symptoms of B12 deficiency itself

Additionally, the neuroprotective effects of MG were observed in various neurodegenerative disorders, including Parkinsons Disease, Alzheimers Disease, Huntingtons Disease, and Amyotrophic Lateral Sclerosis, where once again, Nrf2 activation played a central role [10]

It can also be caused by hormonal changes, medications, or as a normal part of ageing