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These hypotheses have been validated in preclinical models,76 77 98 103 112116 and such agents are now advancing into clinical trials (eg, NCT04330664)

In recent years, various energy-based devicesincluding lasers, intense pulsed light, and radiofrequency deviceshave been increasingly applied in the treatment of melasma, demonstrating both safety and efficacy

Identification and Purification of an Isozyme of A Carboxylase from Rat Heart

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The main sources of sulfur-rich foods are cruciferous vegetables and allium vegetables like onions, garlic, shallots, and leeks