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Despite its significance, the pervasive issue of insomnia plagues a substantial portion of the population, ushering in a host of severe health complications including depression (Riemann et al., 2020), heart disease (Frjd et al., 2021), high blood pressure (Maiolino et al., 2021), and obesity (Knowlden and Grandner, 2021)

Disclosure of interest: All authors: nothing to disclose Poster session I - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.01 - DIAGNOSIS/INVESTIGATION OF STROKE ETIOLOGY P327 - ESOC25-999 MICROEMBOLIC SIGNAL DETECTION: A 5-YEAR EXPERIENCE AT A GERMAN NEUROVASKULAR CENTER Lili Laura Bruta 1 , Irena Kovacic 1 , David Pollinger 2 , David Olmes 2 , Ralf Linker 2 , Felix Schlachetzki 1 1 Center for Vascular Neurology and Intensive Care Medicine (Center II) at the Department of Neurology at the University of Regensburg, Regensburg, Germany, 2 Department of Neurology at the University of Regensburg, Regensburg, Germany Background and Aims: Microembolic signal detection (MES-D) is a potent sonographic biomarker for increased stroke risk but still has no widespread impact on stroke therapy