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Description

Preventing complications and treating symptoms of diabetic peripheral neuropathy

found that carnitine concentrations were low in skeletal and cardiac muscles [84]

writingoriginal draft preparation, M.K

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Individuals with defective carnitine transport have poor intestinal absorption of dietary L-carnitine, impaired L-carnitine reabsorption by the kidneys (i.e., increased urinary loss of L-carnitine), and defective L-carnitine uptake by muscles (4)

Another early study examined hemodynamic and angiographic variables before, during, and after administering intravenous propionyl-L-carnitine (15 mg/kg body weight) in men with myocardial dysfunction and angina pectoris (62)