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They damage cell membranes, proteins, and DNA

Intestinal immune cells, such as macrophages and T cells, undergo significant changes in metabolic pathways during inflammatory states, which not only affect their functional status but also determine the nature and intensity of the immune response

Cho SK, Pedram A, Levin ER, Kwon YJ

It has been shown that alveolar epithelial lining fluid of patients with ARDS is deficient in total GSH compared to normal subjects (107), and neutrophil-mediated oxidants release leads to GSH deficiency and lung cell injury (107)

Mechanisms of PLGA-based nanoparticles transport across the BBB The transport of PLGA-based nanoparticles across the BBB is mediated by active or passive transporters 118