chac1 glutathione Transcriptomic analysis of the effect of (E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl) prop-2-en-1-one (DPP23) on reactive oxygen species generation in MIA PaCa-2 pancreatic cancer cells | Genes & Genomics Frontiers | CHAC1: a master

Frontiers CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death Mammalian proapoptotic factor ChaC1 and its homologues function as glutamyl cyclotransferases acting specifically on glutathione EMBO Reports Springer Nature Link CHAC2 is essential for self renewal and glutathione maintenance in human embryonic stem cells ScienceDirect CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers PMC

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