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In total joint arthroplasty (TJA), wound complications, hematoma formation, and delayed drainage substantially increase susceptibility to periprosthetic joint infection (PJI), an outcome associated with revision surgery, prolonged antimicrobial therapy, and durable functional decline (Xiong et al

Semax and Selank, both small neuropeptides, are traditionally delivered intranasally but have structural characteristics, small molecular weight, relative stability, that support sublingual absorption

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Moreover, UBX0101 reduces significantly oxidative protein stress and displays pro-regenerative response 29

Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease

The second reaction adds a glycine to the Gamma-glutamylcysteine to produce the tripeptide glutathione