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Of note, data on the role of circadian machinery in anti-tumor immunity suggest a possible role of circadian machinery in the development of cold tumors through the accumulation of immune-suppressive cells in the microenvironment and through the regulation of the expression of PDL1 and CTLA4, two major targets of the current immunotherapy 126

Psychiatry 113 TakahashiK.YanaiS.TakisawaS.KonoN.AraiH.NishidaY.et al (2019)

Antioxidants , 10 , 1262

As a major antioxidant, it is maintained in a reduced (GSH) state

Examples of zwitterionic surfactants include cocamidopropyl betaine and sulfobetaine, both of which are valued for their gentle cleansing and foaming capabilities

The procedure for working with animals used to generate the data described in the complied with the ethics standards of facilities involved in investigation (Research Institute of Eye Diseases, Moscow, and Joint Institute for Nuclear Research, Dubna) and was approved by legislative acts of the Russian Federation and international organizations