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FMRP is one of these newly synthesized proteins and serves as a repressor of the translation of other synaptic mRNAs that encode LTD proteins such as activity-regulated cytoskeleton-associated protein (Arc), microtubule associated protein (MAP) 1B and Striatal-enriched protein tyrosine phosphatase (STEP), which mediate a-amino-3-hydroxyl-4-isoxazole propionic acid receptor (AMPAR) internalization and LTD stabilization (Bhakar et al., 2012

elegans lifespan 20 , but this study was limited by indirect measures of iron load, use of only a single dose of deferiprone, and small sample size

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NAR has been used in cosmetic, perfumery, and pharmaceutical products

For example, a review by Gwyer and colleagues (2019) concluded that while studies have reported findings across experimental models, the majority of the evidence comes from laboratory and animal research

Ferroptosis may be one of the pathogenic mechanisms of lumbar intervertebral disc protrusion