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Available human studies are characterized by relatively small sample sizes, heterogeneity in dosing regimens, and short intervention durations, which restrict the ability to draw firm conclusions regarding efficacy and optimal therapeutic windows

Perhaps those individuals have not been able to build a practice large enough to be able to exercise the same option for themselves

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For example, in a feeding trial on YML larvae exposed to DON-spiked diet (groups with increasing content from 2 to 12 mg/kg), the larvae had the same DON content (from 0.122 to 0.136 mg/kg) across all diet groups, unlike the its content in frass which was increasing with the increase of DON the insects diet (Sanabria et al