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All but BMI were within normal range ( Table 2 ), which excludes frequent conditions that may independently cause fatigue (insufficient levothyroxine dose, anemia, diabetes with poor glycemic control, infection)

60 Drug-induced diabetes mellitus Glucocorticoid therapy has been suggested as being a predisposing factor for the development of DM in cats

Increased TMAO levels are caused by lower clearance and increased synthesis as a result of gut dysbiosis, a weakened intestinal barrier, and increased hepatic enzyme activity

The resulting supernatant was analyzed using high-performance liquid chromatography (HPLC, VWR Hitachi, Radnor, Pennsylvania, USA) coupled with mass spectrometry (3200 Q Trap, AB Sciex, Framingham, Massachusetts, USA) to quantify the target compounds

doi:10.1196/annals.1320.003

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