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Some case series did not perform additional testing for non-conventional autoantibodies [5, 18, 178], while others conducted extensive antibody panels, including anti-LC-1, anti-SLA, myeloperoxidase-anti-neutrophil cytoplasmic antibody, anti-mitochondrial, anti-tissue transglutaminase, and anti-platelet antibodies, though in varying order [31, 177, 179]

Wirth JJ, Fraker PJ, Kierszenbaum F

5.2 cGAS-STING is a potential target that links oxidative stress and viral infection It is widely known that the invading DNA virus will activate the cGAS-STING pathway, inducing type I IFN production and causing a range of innate immune responses

Feng Y, Jia Y, Su L et al (2013) Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatonin

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Rho GTPases in Brain Diseases Considering the critical roles of Rho GTPases in spine formation and morphology, synaptic plasticity, and memory, it is not surprising that dysfunctions in these proteins are linked to various brain diseases, some of which will be briefly discussed below