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The resulting digested ECM solution was then aliquoted, frozen at 80 C, and subsequently lyophilized for 48 hours

Spectra were processed with NMRPipe (v2.0) 45 and analyzed using NMRVIEW (v5.0) 46

The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress

These villi are finger-like projections that increase the guts absorptive surface

Here, we will (a) examine approaches to elucidate the GCN2methionineROS circuit to determine what forms of therapeutic modulation for T cell immunotherapies may be beneficial in a given context, and (b) explore different nodes within the GCN2-methionine-ROS circuit where intervention may be advantageous

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