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Description

Following perfusion, the brain was fixed for 48 hours and embedded in paraffin

Each peptide has specific stability requirements, and combining them can cause aggregation, degradation, or altered pharmacokinetics

Additional plateable PHHs Hum180931 (Lonza, catalog: HUCPI) were thawed and plated in hepatocyte plating medium (Lonza, catalog: MP250) overnight, then the medium was replaced with hepatocyte culture medium (Lonza, catalog: CC-3198)

Although there are data in animal models supporting that this is true, particularly in diet-induced obese mice, in which brown adipose tissue activity is regulated [8], there is no convincing evidence that this occurs in humans [6]