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214 Alzheimers disease (AD) Alzheimers disease (AD) is characterized by senile plaques and neurofibrillary tangles (NFTs) caused by amyloid- and phosphorylated tau deposition

However, our study provides a future direction for investigating the underlying mechanism of PA modifying heavy metal exposure to H pylori infection

**, Pedelacq, J.-D

Specifically, neuromelanin impairs the UPS by inhibiting the enzymatic activity of the 26S proteasome [19]

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