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This patient's Parkinson disease motor fluctuations stem from nigrostriatal dopamine depletion, making an adrenal enzyme involved in systemic epinephrine synthesis irrelevant to his required treatment

Pathology 54:104110 Di Martino MT, Leone E, Amodio N, Foresta U, Lionetti M, Pitari MR, Cantafio MEG, Gull A, Conforti F, Morelli E (2012) Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo EvidenceAntitumor Activity of miR-34a in Multiple Myeloma

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Cell 178:1102-1114e1117 Cignarella F, Cantoni C, Ghezzi L, Salter A, Dorsett Y, Chen L, Phillips D, Weinstock GM, Fontana L, Cross AH, Zhou Y, Piccio L (2018) Intermittent fasting confers protection in CNS autoimmunity by altering the gut microbiota

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