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In REDEFINE 1 , a 68-week, Phase 3a, multicenter, double-blind, placebo- and active-controlled trial, 3,417 adults with overweight or obesity but without diabetes were randomized to CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg), semaglutide 2.4 mg, cagrilintide 2.4 mg, or placebo

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Hereditary Diffuse Gastric Cancer (HDGC) is one type of stomach cancer that is sometimes caused by a mutation in the CDH1 gene

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By activating GLP1 receptors more strongly and for longer, semaglutide: Slows gastric emptying (food leaves your stomach more slowly)