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Description

Neonatal clinicians should be aware of the current US Food and Drug Administration safety warning in the pediatric population based on a dose escalation pediatric trial (all infants were older than 1 year) that demonstrated a higher mortality in the high-dose group (73)

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Thus, the ineffective shut-down of housekeeping processes during chaperone induction due to macromolecular assembly defects often results in less-than-optimal performance [156]