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Pharmaceutics 14: Bonner JJ, Burt H, Johnson TN et al (2021) Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency

The gene expression of the proneural subtype, including the receptor tyrosine kinase (RTK) I/LGm6 DNA methylation group, exhibiting molecular alterations such as cell cycle-dependent kinase 4 (CDK4) and platelet-derived growth factor receptor alpha (PDGFRA) amplification, predominates among younger adults