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In the control group, an equivalent amount of saline was used

For the neuronal culture, hippocampi were dissected in HBSS, and digested for 1 h at 37 C in DMEM supplemented with 25 U/ml papain (Worthington Biomedical Corp., USA), 0.2 mg/ml cysteine (Merck, Germany), 1 mM CaCl 2 , and 0.5 mM EDTA

The most common MTHFR mutation is called C677T, and it can cause a decrease in MTHFR enzyme activity by up to 70%

Each component contributes a distinct and complementary mechanism of action, making KLOW a subject of interest in multi-pathway research models

84 Reduction in Nrf2 activity and a corresponding decrease in these enzymatic antioxidants have been observed in the retina of diabetic patients

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