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A thinner needle (higher gauge) causes less discomfort but draws medication more slowly, which is why many patients use a wider drawing needle and switch to a thinner needle before injecting

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Toxicol Sci 2016;154:21426 [DOI] [PMC free article] [PubMed] [Google Scholar] 24.Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H.The impact of partial manganese superoxide dismutase (SOD2) deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity

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Talk to your doctor or endocrinologist about safe ways to alter your current medications to safely incorporate these injections into your regimen