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The best characterized stimuli are patterns of neuronal electrical activity like prolonged depolarization, high-frequency stimulation (HFS), or theta-burst stimulation (TBS) that trigger BDNF release in developing and mature neurons (Edelmann et al

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50 Atypical antipsychotics, including risperidone (a dopamine antagonist) and aripiprazole (a dopamine agonist), are FDA-approved drugs that have been shown to relieve irritability symptoms such as aggression and self-mutilation in adolescent autistic patients in several large clinical trials

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