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Supplementary material The Supplementary Material for this article can be found online at: Abbreviations AEs, Adverse events

The presence of salt ions in solution can lead to the partial unfolding of a protein and the exposure of normally buried hydrophobic residues

The content of analytes IFN-, TNF-, and cAMP was measured using ELISA kits according to the manufacturer's instructions

Huang et al., 2024

Furthermore, the salivary secretions, gastrointestinal mucosal secretions and factors of intra-luminal microflora jointly preserve the normal homeostasis (28, 29)