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While leukotrienes are secreted from senescent cells, they appear to function in parallel to SASP factors (Hamsanathan and Gurkar, 2022)

Oxidative stress is a consequence of an imbalance between the production of ROS and antioxidant agents

Paleolithic diet, which excludes hyperglycemic carbohydrates and insulinotropic dairy, has been successfully introduced for the prevention and treatment of acne, T2D and cardiovascular diseases [16, 29]