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This modulation of inflammatory signaling occurs through activation of the PI3K/AKT pathway, which possesses intrinsic anti-inflammatory properties including inhibition of pro-inflammatory cytokine release and enhancement of cellular stress resistance

While limited evidence supports this, the practice is common

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8c, f, Supplementary Figs

2017 Cell study, with subsequent independent confirmations in human chondrocytes (Huang 2021), mouse Leydig cells (Zhang 2020