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This partial information can lead to our GPs thinking that B12 deficient patients without a confirmed diagnosis of PA do not require treatment by injection

The National Institute for Health and Care Excellence (NICE) notes that the prevalence of Vitamin B12 deficiency is approximately 6% in those under 60 years old, rising to 20% in the over 60s

Cyanocobalamin is commonly used in supplements and is considered highly effective for most individuals

Microdosing is a drug administration method involving significantly lower doses than are typically used for therapeutic effects

We recommend future research directions to determine when to start with SL, IM, or oral vitamin B12 in different situations

Kinase-substrate relationships were obtained from the PhosphoSitePlus database and provided as gene sets (PhosphoSitePlus)