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No antiviral agents to manage DENV infections are yet licensed and the clinical benefit of the available tetravalent DENV vaccines, Dengvaxia and Qdenga, are limited by safety concerns and inconsistent long-term efficacy across the four DENV serotypes (Sridhar et al., 2018)

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ELF values close to 1 (red regions) indicate highly localized electron pairs, whereas lower values (blue regions) correspond to delocalized or depleted electron density

Loss of colour over time can indicate degradation or copper dissociation, so storage protocols matter

WADAs S0 classification covers any pharmacological substance not approved for human use by a governmental health authority , meaning a positive test could result in sanctions regardless of whether the compound is directly listed

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