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This includes your skin, too

Iron-deficiency anemia also lowers your blood's oxygen-carrying capacity, forcing your heart to pump faster and harder to compensate

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Affecting approximately 50% of patients with diabetes, DN is predominantly characterized by distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, often resulting in diabetic foot ulcers and lower-limb amputations

From Our Lecture Notes: The hypothalamus acts as the master hormonal regulator , influencing stress, hunger, reproduction, and circadian rhythm