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Browne and Beal 2006)

The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-kappaB signaling

Kadara H, Choi M, Zhang J, Parra ER, Rodriguez-Canales J, Gaffney SG, Zhao Z, Behrens C, Fujimoto J, Chow C, Yoo Y, Kalhor N, Moran C, Rimm D, Swisher S , Gibbons DL, Heymach J, Kaftan E, Townsend JP, Lynch TJ, Schlessinger J, Lee J, Lifton RP, Wistuba II, Herbst RS

W.DetmarM.AjiokaI.DvorakH

The study concluded that probiotics reduced gut leakiness, lowered oxidative stress, and enhanced GABA-receptor expression, supporting a protective role on the gut-brain axis in this ASD model

Two thousand and sixty-five hepatitis B antigen-positive men from Qidong were randomised into two groups: 1112 received 05 mg Se/d (as sodium selenite) and 953 men received a placebo (Reference Li, Zhu and Yan31)