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Collins team had already discovered that antibiotics that kill bacteria do so by triggering oxidative stress in the bacteria

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) ME/CFS is defined as persistent or relapsing fatigue for at least six months, which is not resolved by rest, and causes a substantial reduction in the Activity of Daily Living (ADL) 206

Cleared by FDA

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All discussions of synergy are currently based on theoretical models and preclinical data for each compound individually

Front Plant Sci 5:488 Arnaud D, Hwang I (2015) A sophisticated network of signalling pathways regulates stomatal defences to bacterial pathogens