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Contrave, designed for oral administration, has variable bioavailability: naltrexone reaches about 96% bioavailability, while bupropion achieves approximately 87% bioavailability when taken with food

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In comparing the two formulations, the Sucrosomial B12 group consistently exhibited higher circulatory vitamin B12 levels at every post-treatment timepoint ( p 0.029) (Figure 4 boxplots, bottom)

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