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TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

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both dry and exudative subjects were investigated ( A recent multicentered retrospective study involved thousands of inpatient and outpatient subjects in the US who either had no evidence of AMD at the onset of the investigation or were previously diagnosed with the condition ( Despite strong support from experimental studies, the evidence of melatonins ability to alter the onset or progression of human AMD is inadequate to make a definitive judgment about the significance of daily melatonin use in resisting this devastating condition

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Competing interests The authors have no relevant affiliations or financial involvement with any organization or entity with the financial interest or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed