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To explore whether targeted intervention of Chac2 in neutrophils could alleviate the inflammatory comorbidity of periodontitis, we constructed AAV9 viruses targeting neutrophils to specifically knock down Chac2 (AAV-shCHAC2) and a control virus with no payload (AAV-NC), and administered them via intraosseous injection into a mouse model with periodontitis and diabetes comorbidity

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Supporting information ACKNOWLEDGEMENTS The authors wish to thank L'Oreal Active Cosmetics for providing funding for medical writing support from Valerie Sanders, Sanders Medical Writing

its enabling the activity that burns the fat

Eat sulfur-rich foods like broccoli, kale, and garlic, which provide the building blocks for glutathione