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Limit duration of use so the total combined duration of oral and parenteral ketorolac does not exceed 5 days because of the increased risk of serious adverse events

10.1136/bmj.i4919 [DOI] [PMC free article] [PubMed] [Google Scholar] Sterne J

4.3 Pharmacokinetic parameters in Sprague-Dawley rats after intravenous and intramuscular administration A total of 324 SD rats were randomly divided into five groups, including 66 rats in group one, 60 rats each in groups two to four, and 78 rats in group five, with each group comprising half male and half female subjects