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The lung has natural defense mechanisms and a considerable capacity to repair itself, but the working of these mechanisms may be affected by genetic traits (e.g., alpha-1 antitrypsin deficiency) or exposure to other environmental risk factors (e.g., infection, atmospheric pollution) 75 , as well as by the chronic nature of the inflammation and repeated nature of the injury

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Access this article Similar content being viewed by others References Agudelo-Romero P, Erban A, Rego C, Carbonell-Bejerano P, Nascimento T, Sousa L, Martnez-Zapater JM, Kopka J, Fortes AM (2015) Transcriptome and metabolome reprogramming in Vitis vinifera cv