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Antioxidant vitamins, C and E, or pomegranate juice, can increase PON1 levels.[ref] For people with the PON1 variant, you may want to consider how many antioxidant-rich foods you eat each day

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(c) case-control studies

HBOT-induced ROS generation may initiate adaptive signaling pathways that promote angiogenesis, tissue repair, and cellular survival, whereas excessive ROS accumulation contributes to oxidative damage and impaired microcirculation

Vitamin B12 may be part of the picture, but lifestyle factors, stress, sleep quality, and other health issues can also play a role

The clinical stroke protocol of 10 days reflects this timeline