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5.2 Treatment The therapeutic arsenal for alleviating muscle cramps in cirrhosis spans a variety of agents, including vitamin E, pregabalin, intravenous albumin, eperisone, taurine, zinc, baclofen, methocarbamol, orphenadrine, branched-chain amino acids, L-carnitine, and quinidine

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Analysis of these structures provide context for how a number of variants associated with SPCD affect the transport of carnitine

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Interestingly, oleuropein aglycone a polyphenol abundantly present in extra virgin olive oil is reported to induce autophagy in AD mouse models by modulating AMPK signaling (288, 289) as well as sirtuin activity and histone acetylation (288)