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found that Erchen Decoction can also reduce levels of inflammatory factors (such as TNF- and IL-1) and enhance the mucosal barrier (e.g., by increasing ZO-1 levels)

Frequently, the predetermined antigen is a human protein, such as for example a human cell surface antigen (e

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& Lischer, H

Alkylamine-based degraders functionally depend on FBXO22 To explore the potential generalizability of exploiting FBXO22 for targeted protein degradation, we extended our experiments to two recently reported primary alkylamine-tethered degraders targeting either NSD2 or XIAP, as well as a set of alkylamine-tethered analogues targeting BRD4 (Fig