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Journal of Clinical Gastroenterology, 51 (1), e5-e10

Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials

Foxo3 is required for the regulation of oxidative stress in erythropoiesis

This method allows for rapid and efficient absorption of substances, bypassing the digestive system, and ensuring they reach their intended targets in the body quickly

This modification, known as an omega-amino acid modification, may help improve the peptides resistance to enzymatic degradation

A plausible explanation could be a reorientation of Lys105 towards GS resulting in a decreased stabilization of the active site thiolate as a leaving group