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Activation of macrophages, in turn dysregulates the immune-inflammatory pathways viz

DNA was isolated using the Qiagen Plasmid Mini kit or the Qiagen Plasmid Plus Midi kit

PLoS ONE 2:e1322 Spitz MR, Duphorne CM, Detry MA et al (2000) Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk

Cell 31 , 347359 (2008)

Clinical studies in AD patients have reported favorable changes in disease-related biomarkers with KD, including increased CSF A (reflecting reduced cortical deposition) and significantly decreased tau levels [105, 106]