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doi: 10.1016/j.redox.2017.08.007 148

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Mutations in genes affecting the production of this enzyme can have a significant impact on the function of the MTR enzyme and thus recycling of homocysteine back into methionine (13)

[346] Conversely, saturated and trans fats, excessive alcohol, high-sugar and high-glycemic-index foods, and metabolic diseases like diabetes and obesity can increase cataract risks, making proper management through diet, exercise, and medication vital for risk reduction

Moreover, UMOD overexpression correlates with diminished UA excretion, renal fibrosis, immune cell infiltration, and progressive renal failure

Jika hal tersebut terjadi, maka bisa mengakibatkan kulit rusak serta menimbulkan tanda-tanda penuaan, seperti munculnya kerutan serta garis halus di wajah