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10.1016/j.neuint.2011.06.011 326 ReissnerK

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TMAO has been shown to affect the cytotoxicity of NK cells

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Zheng S, Liu Y, Li P, Tian H

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Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

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However, due to the small nature of the molecule, TMA is difficult to fragment using tandem mass spectrometry, and there are not many reports of LC-MS being used to measure TMA

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These findings suggest that while TMAO may contribute to metabolic disturbances (e.g

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