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In a mouse model, these liposomes exhibited superior penetration capabilities and led to a significant reduction in cutaneous eosinophil count, erythema, and irritation compared to commercially available ointments and creams [113, 114]

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When human uterine leiomyoma cells were being treated with SB, it was observed that c-fos mRNA expression was being induced by SB via the cAMP/PKA pathway which was activated by the increased in cAMP level (Lee et al., 2004a)

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