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According to the National Institutes of Health (NIH), vitamin B12 supports a healthy central nervous system, red blood cell formation, and the synthesis of genetic material like DNA [1]

Interestingly, the presence of functional microglia in brain slices [53] or in human cortical organoids attenuated the A-mediated induction of ferroptosis [50]

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Mass spectrometry (MS) is regarded as the gold standard in metabolomic investigations, owing to its exceptional sensitivity, mass resolution, and metabolite coverage ( Table 1 )