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For someone who wants a minimally invasive addition to their existing diet and exercise program, the risk-to-reward ratio is very low because the risks are essentially zero

Studies on MOTS-c highlight its role in mitochondrial signaling, insulin sensitivity, and metabolic regulation

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Laboratory studies in cell and animal models of accelerated aging have shown that replenishing NAD+ can restore mitochondrial function and stimulate beneficial cellular recycling processes like mitophagy