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Description

Auchincloss, M

Esto evidencia un cambio en la velocidad de sntesis y en el recambio del GSH (Figura 2) (30)

The stimulation of Cdk5 results in the generation of ROS, which leads to cell death due to a feedback mechanism

its strategy

As single agents, APR-246 and system x C inhibitors exploit this vulnerability to selectively target mut-p53 cancer cells in a synthetic lethal-like fashion